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ML-9 hydrochloride
CAS No. 105637-50-1
ML-9 hydrochloride( ML9 | ML-9 | ML 9 )
Catalog No. M10258 CAS No. 105637-50-1
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 47 | Get Quote |
|
| 25MG | 87 | Get Quote |
|
| 50MG | 142 | Get Quote |
|
| 100MG | 212 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameML-9 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
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DescriptionML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines; also inhibits PKA and PKC with Ki of 32 and 54 uM; inhibits STIM1-plasma membrane interactions and inhibits TRPC6 channels via a mechanism independent of inhibition of MLCK activity.
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In Vitro——
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In Vivo——
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SynonymsML9 | ML-9 | ML 9
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMyosin
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RecptorMyosin
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Research Area——
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Indication——
Chemical Information
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CAS Number105637-50-1
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Formula Weight361.281
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Molecular FormulaC15H18Cl2N2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (230.65 mM)
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SMILESO=S(N1CCNCCC1)(C2=C3C=CC=C(Cl)C3=CC=C2)=O.[H]Cl
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Chemical Name1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-1H-1,4-diazepine, monohydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shi J, et al. Br J Pharmacol. 2007 Sep;152(1):122-31.
2. Várnai P, et al. Trends Pharmacol Sci. 2009 Mar;30(3):118-28.
3. Ito S, et al. Eur J Pharmacol. 2004 Feb 23;486(3):325-33.
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ML-9 hydrochloride
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
